Calcium Pyrophosphate Dihydrate Disease or CPPD is serious disease that results from the build up of calcium crystals in the bone joints. CPPD is associated with in joint inflammation that causes serious pain. If this is not treated on time, it may damage the tissues inside the bones and the joint and lead to disability.
Though the exact causes are not yet known, the genes are held responsible for the formation of calcium phosphates inside the joints. Hypothyroidism can also be responsible for this disease. Other factors include presence of excess iron, low magnesium, previous joint damage and osteoarthritis. There are five presentations of CPPD and they along with their Symptoms of Calcium Pyrophosphate Dihydrate are as follows.
Symptoms Of Calcium Pyrophosphate Dihydrate
This is the most common form of CPPD presentation and affects the knee mostly though symptoms can be felt along both sides of the body. One side of the body is severely affected. The joints begin to degenerate that becomes worse with time.
Joint degeneration is accompanied by deformity and misalignment as well. There can even be swelling and inflammation also. These swelling are at times chronic and are associated with pain and discomfort. The knee joint can get deformed in severe cases.
Less than 5% of the CPPD patients get affected by this presentation of CPPD. The earliest and common Symptoms of Calcium Pyrophosphate Dihydrate is seen in the knees. There is no neurological disorder as such and the presence of calcium phosphates makes it easy for diagnosis. There can be severe pain and this presentation of CPPD is basically destructive arthropathy. Though the knee is mostly affected, the other joints can also be affected by this.
This also affects the knees in most cases but is known to affect the other joints of the body as well. Some times pseudogout is not associated with any kinds of Symptoms of Calcium Pyrophosphate Dihydrate and sometimes symptoms become visible only after a certain surgery or temporary illness.
There can be sudden and intensifying pain in the joints. The joints swell up and become reddish and warm. There can also be fever and the fracture of the cartilages which can be immensely painful.
Asymptomatic (lanthanic) CPPD
This is associated with the formation of calcium phosphates in the hyaline and fibro cartilages present in the knees and also fibro cartilage present in the wrist ligament. The joints that are present in the pubis and the hips can also affected by this presentation of CPPD. This is also quite common and is associated with pain and swelling as well. The acetabulum labrum is present in the hips which get affected.
This is the most uncommon presentation of CPPD. This is known to affect both the sides of the body. The patients suffer from morning stiffness and fatigue. There is also swelling in the joints and if the swelling is in the knee joint, the patients find it difficult to walk.
There can joint deformities as well. There is inflammation in the PIP joint and the MCP joint. The patients are also known to suffer from acute swelling in the joints.