The chronic inflammatory disease affecting the joints between the bones of the spine is known as ankylosing spondylitis. It can also target the joints between the pelvis and the spine. Movements of a patient suffering from this disease are restricted and this immobilization gradually leads to fusion of vertebrae and permanent disability.
Infliximab is a well known drug that has shown some promising improvement in the individuals suffering from this disease. In United States, this drug is marketed as Remicade. In this post, we are going to discuss more about remicade treatment for ankylosing spondylitis.
Treatments for Ankylosing Spondylitis
Remicade is highly used for the treatment of autoimmune disorders like ulcerative colitis, Crohn’s disease, psoriasis, ankylosing spondylitis and psoriatic arthritis. In 1998, the Food and Drug Administration approved the usage of remicade for the treatment of Crohn’s disease.
You cannot take remicade orally. This is because the drug will get destroyed in the gastrointestinal tract. For this reason, it is intravenously introduced inside the body of a patient suffering from ankylosing spondylitis, after every 7 or 8 weeks.
We have already come to know that remicade is a treatment that helps to reduce the symptoms of ankylosing spondylitis. The dosage of this drug is also mentioned earlier, but we are still ignorant about the internal functioning of the drug that leads to eradication of the irritating symptoms.
When remicade is introduced inside the body, it acts as a chemical blocker to block the messengers that stimulates autoimmune reaction. By shutting down the autoimmune response, the patient is relieved of the symptoms of ankylosing spondylitis for a longer period of time. In a study conducted with patients suffering from this disease were treated with this drug and they showed improvement within 2 weeks.
Just like any other synthetic drugs, the remicade treatment may also lead to negative outcomes. Though the drug is effective enough to suppress the symptoms of ankylosing spondylitis within a short period of time, but it is immunosuppressive in nature. Patients who are taking these drugs may alleviate the painful symptoms, but they become more vulnerable to infections.
Moreover, with the functioning of the immune system suppressed, it becomes even harder to treat the newly developed infections. There are many people who are consuming this drug over a long period of time despite its immunosuppressive property and this leads to building up of resistance to this drug.
As far as long term treatments are concerned, regular exercises and food remedies are usually recommended by the physicians to patients suffering from ankylosing spondylitis. If the symptoms are quite severe, the doctors may even suggest surgery, but they do not prescribe remicade as alternative medication.
This is because remicade has several side effects like abdominal pain, nausea, runny nose, cough, sneezing, dizziness, nasal congestion, wheezing, headache, sore throat, muscle pain, shortness of breath, weakness and intolerable tightness in the chest. At times, the side effects of remicade can be even more irritating like causing fainting or vomiting sensations all of a sudden.
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