Juvenile Vaculitis is a syndrome that affects kids, causing swelling in their blood vessels. Due to the inflammation, the blood vessels tend to become weak and may either increase or narrow down in size. The blood vessels may even close forever because of the inflammation. Juvenile vasculitis may affect any blood vessel in the entire body including the arteries, vein or venules.
In the advanced stages, this syndrome can lead to several complications such as heart attack or aneurism of arteries. In some extreme cases, this disorder may prove to be fatal. This syndrome may affect only specific organs of the body such as only the eyes, brain, or skin. However, in some cases it can affect several organs at once. Juvenile Vasculitis may be mild for some, where as severe for others. The exact cause of Juvenile Vasculitis is not known but it is believed to be associated with genetic predispositions and weak and dysfunctional immune system.
Main Causes of Juvenile Vasculitis
One of the most common causes of Juvenile Vasculitis is the misdirected immune system, which unfortunately tends to misunderstand the healthy tissues as a threat to the body and attack to destroy them. Instead of saving the body from several foreign invaders, it causes great harm, often causing the vasculitis in children. It is observed that kids who have weak immunity are more susceptible to developing Juvenile Vasculitis.
Kids bearing genes, inherited from parents with Vasculitis become prone to developing Juvenile Vaculitis. Genetics play a tremendous role in triggering this disorder in children who have genetic predispositions.
Hypersensitivity reaction occurs when a person who was suffering from one chronic disease recovers, but the already sensitized body again gets exposed to the same antigen, causing hypersensitivity of the immune system. This may cause serious injury of the tissues, extreme shock or even death. Some of the diseases that may be a source of hypersensitivity reaction in the body include the Systemic lupus erythematosus, commonly known as the SLE, and Wegener’s Granulomatosis.
Reaction to Medications
Many times children treated with some drugs to recover from fatal diseases can become vulnerable to developing juvenile vasculitis. The drugs used to cure one disorder, sometimes lead to initiate another disease in the body. This is completely true with this disorder, making it one of the main causes of vasculitis in children. It is observed that children fighting rheumatoid arthritis or diabetes tend to develop this chronic disease often as a reaction to the medication used to cure these diseases.
Rheumatoid arthritis can also lead to Juvenile vasculitis, causing inflammation of the blood vessels in different organs of the body. This syndrome may be related to a chronic disease that a child may have suffered from for several years. Rheumatoid arthritis is one of those diseases that can lead to juvenile vasculitis.
Juvenile vasculitis may sometimes develop after a child has suffered and recovered from an infection. These infections usually trigger a strange response in the immune system of the child, leading to an absolute damage of the blood vessels.